Find flights
Airlines

R10 164+ Cheap flights from Panama City

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/7. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — JNB
Apr 7 — Apr 141
1 adult

What to know about flights from Panama City

Discover essential information about flights departing from Panama City, including flight schedules, destinations, airlines operating at the Panama City airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 2 April 2025.

Cheapest airline

United Airlines

Good round-trip deal

R18 620 or less

Good one-way deal

R2 936 or less
On average, United Airlines currently has the cheapest one-way flight from Panama City Tocumen Intl (avg. price of R26 801).
Search Deals
Price to beat on a round-trip flight from Panama City Tocumen Intl.
Search Deals
Price to beat on a one-way flight from Panama City Tocumen Intl.
Search Deals

Find flights from Panama City

Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 2 April 2025.

Wed 23/412:56PTY - JNB
2 stops45h 49mUnited Airlines
Wed 7/519:00JNB - PTY
2 stops42h 13mUnited Airlines
Deal found 1/4R19 225
Fri 16/58:02PTY - CPT
2 stops42h 28mUnited Airlines
Fri 23/518:05CPT - PTY
2 stops43h 32mUnited Airlines
Deal found 1/4R26 576
Wed 23/421:55PTY - JNB
1 stop29h 40mTurkish Airlines
Wed 7/517:55JNB - PTY
2 stops31h 25mTurkish Airlines
Deal found 1/4R30 822
Fri 16/513:30PTY - CPT
2 stops34h 40mMultiple Airlines
Fri 23/516:35CPT - PTY
3 stops33h 05mMultiple Airlines
Deal found 1/4R32 366
Fri 16/520:00PTY - CPT
1 stop32h 50mTurkish Airlines
Fri 23/516:35CPT - PTY
2 stops32h 45mTurkish Airlines
Deal found 1/4R33 138
Wed 16/418:50PTY - JNB
1 stop43h 30mKLM
Wed 2/723:15JNB - PTY
1 stop24h 35mKLM
Deal found 1/4R37 641
Fri 16/518:50PTY - CPT
1 stop43h 35mKLM
Fri 23/523:15CPT - PTY
1 stop24h 35mKLM
Deal found 1/4R47 198
Wed 23/411:43PTY - JNB
3 stops45h 32mEmirates
Wed 7/513:25JNB - PTY
3 stops52h 03mEmirates
Deal found 1/4R51 499
Fri 18/721:55PTY - JNB
1 stop29h 40mMultiple Airlines
Fri 1/818:30JNB - PTY
2 stops43h 11mMultiple Airlines
Deal found 1/4R140 675
Sun 1/613:20PTY - JNB
3 stops34h 40mAmerican Airlines
Sun 8/621:15JNB - PTY
2 stops46h 45mAmerican Airlines
Deal found 1/4R190 520

Find flights from Panama City within your budget

Find flights departing from Panama City that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 2 April 2025. In the last 7 days, Cheapflights users made a total of 594 507 searches

Fly to

OR Tambo

Route

Depart

Return

Price

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Wed 23/4

12:56-17:45

2 stops45h 49m

Johannesburg OR Tambo

Wed 7/5

19:00-6:13

2 stops42h 13m

R19 225

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Fri 16/5

8:02-9:30

2 stops42h 28m

Cape Town Intl

Fri 23/5

18:05-6:37

2 stops43h 32m

R26 576

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Wed 23/4

21:55-10:35

1 stop29h 40m

Johannesburg OR Tambo

Wed 7/5

17:55-18:20

2 stops31h 25m

R30 822

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Fri 16/5

13:30-7:10

2 stops34h 40m

Cape Town Intl

Fri 23/5

16:35-18:40

3 stops33h 05m

R32 366

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Fri 16/5

20:00-11:50

1 stop32h 50m

Cape Town Intl

Fri 23/5

16:35-18:20

2 stops32h 45m

R33 138

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Wed 16/4

18:50-21:20

1 stop43h 30m

Johannesburg OR Tambo

Wed 2/7

23:15-16:50

1 stop24h 35m

R37 641

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Fri 16/5

18:50-21:25

1 stop43h 35m

Cape Town Intl

Fri 23/5

23:15-16:50

1 stop24h 35m

R47 198

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Wed 23/4

11:43-16:15

3 stops45h 32m

Johannesburg OR Tambo

Wed 7/5

13:25-10:28

3 stops52h 03m

R51 499

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Fri 18/7

21:55-10:35

1 stop29h 40m

Johannesburg OR Tambo

Fri 1/8

18:30-6:41

2 stops43h 11m

R140 675

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sun 1/6

13:20-7:00

3 stops34h 40m

Johannesburg OR Tambo

Sun 8/6

21:15-13:00

2 stops46h 45m

R190 520

Flights are sorted by cheapest return flights first.

Deals found on 1/4

Showing 1-10 of 16 results
1
2

Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City

Get recent, data-driven insights about flights from Panama City including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama City?

Currently, November is the cheapest month in which you can book a flight from Panama City (average of R19 004). Flying from Panama City in August will prove the most costly (average of R31 079). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

Which airlines fly from Panama City?

When flying from Panama City check dates and pricing for the following: United Airlines. As it departs for the following popular destinations: Johannesburg.

United Airlines

United Airlines

From R1 033

What are popular destinations to fly to from Panama City?

From Panama City you can expect to find greater availability for the following destinations: Sao Paulo (224 flights per day), San José (84 flights per day) and Guatemala City (66 flights per day).

Quito Mariscal Sucr

Quito Mariscal Sucr

From R160

Madrid Barajas

Madrid Barajas

From R1 013

What is the cheapest place to fly to from Panama City?

The cheapest city to fly to from Panama City is Quito Mariscal Sucr, with prices starting at R2 936. Explore other affordable destinations below.

Quito Mariscal Sucr

Quito Mariscal Sucr

From R160

Madrid Barajas

Madrid Barajas

From R1 013

Airline reviews for flights from Panama City

Get insights into the airlines that provide service from Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing airline for your flight from Panama City. In the last 7 days, Cheapflights users made a total of 594 507 searches.
Emirates
8,0
Very Good
3 193 reviews
Check prices

Boarding

8,1

Comfort

8,0

Food

7,8

Entertainment

8,2

Crew

8,3

Overall

8,0

Reviews

1 / 20
2,0
Mediocre

Ahmad wadah,Jan 2024

CAI - DXB

Unfortunately, I have arrived to Bangkok yesterday morning and no bag . I have checked with EK staff many times to get the confirmation that , my bag is on the flight . They have confirmed so but the reality was totally opposite. I am here for business trip and I have several meetings . Imagin !!!!! Till this time , they are telling me that : bag not yet found . This is my experience
Emirates
8,0
Very Good
3 193 reviews
Emirates
8,0
Very Good
3 193 reviews
Check prices

Boarding

8,1

Comfort

8,0

Food

7,8

Entertainment

8,2

Crew

8,3

Overall

8,0

Reviews

1 / 20
2,0
Mediocre

Ahmad wadah,Jan 2024

CAI - DXB

Unfortunately, I have arrived to Bangkok yesterday morning and no bag . I have checked with EK staff many times to get the confirmation that , my bag is on the flight . They have confirmed so but the reality was totally opposite. I am here for business trip and I have several meetings . Imagin !!!!! Till this time , they are telling me that : bag not yet found . This is my experience
Delta
8,0
Very Good
7 897 reviews
Emirates
8,0
Very Good
3 193 reviews
Check prices

Boarding

8,1

Comfort

8,0

Food

7,8

Entertainment

8,2

Crew

8,3

Overall

8,0

Reviews

1 / 20
2,0
Mediocre

Ahmad wadah,Jan 2024

CAI - DXB

Unfortunately, I have arrived to Bangkok yesterday morning and no bag . I have checked with EK staff many times to get the confirmation that , my bag is on the flight . They have confirmed so but the reality was totally opposite. I am here for business trip and I have several meetings . Imagin !!!!! Till this time , they are telling me that : bag not yet found . This is my experience
KLM
7,8
Good
1 323 reviews
Emirates
8,0
Very Good
3 193 reviews
Check prices

Boarding

8,1

Comfort

8,0

Food

7,8

Entertainment

8,2

Crew

8,3

Overall

8,0

Reviews

1 / 20
2,0
Mediocre

Ahmad wadah,Jan 2024

CAI - DXB

Unfortunately, I have arrived to Bangkok yesterday morning and no bag . I have checked with EK staff many times to get the confirmation that , my bag is on the flight . They have confirmed so but the reality was totally opposite. I am here for business trip and I have several meetings . Imagin !!!!! Till this time , they are telling me that : bag not yet found . This is my experience
United Airlines
7,4
Good
8 616 reviews
Emirates
8,0
Very Good
3 193 reviews
Check prices

Boarding

8,1

Comfort

8,0

Food

7,8

Entertainment

8,2

Crew

8,3

Overall

8,0

Reviews

1 / 20
2,0
Mediocre

Ahmad wadah,Jan 2024

CAI - DXB

Unfortunately, I have arrived to Bangkok yesterday morning and no bag . I have checked with EK staff many times to get the confirmation that , my bag is on the flight . They have confirmed so but the reality was totally opposite. I am here for business trip and I have several meetings . Imagin !!!!! Till this time , they are telling me that : bag not yet found . This is my experience
Turkish Airlines
7,3
Good
3 748 reviews
Emirates
8,0
Very Good
3 193 reviews
Check prices

Boarding

8,1

Comfort

8,0

Food

7,8

Entertainment

8,2

Crew

8,3

Overall

8,0

Reviews

1 / 20
2,0
Mediocre

Ahmad wadah,Jan 2024

CAI - DXB

Unfortunately, I have arrived to Bangkok yesterday morning and no bag . I have checked with EK staff many times to get the confirmation that , my bag is on the flight . They have confirmed so but the reality was totally opposite. I am here for business trip and I have several meetings . Imagin !!!!! Till this time , they are telling me that : bag not yet found . This is my experience

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Direct flights from Panama

Book a direct flight from one of these other cities located in Panama.
Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 2 April 2025.

  • What are the most popular destinations to fly to from Panama City?

    The most selected flight destinations from Panama City for the current month are Bogotá, Cartagena, Bocas del Toro. While Bogotá, Cancún, Cartagena are the top choices made by travellers year-round.

  • What is the cheapest flight from Panama City to anywhere?

    Users have flown out of Panama City for as low as R2 936 to Quito (prices may vary depending on the airline and departure time). On average, users have booked flights for R10 778 to fly from Panama City.

  • What is the cheapest month to fly from Panama City?

    November is currently the cheapest month to fly from Panama City. At this moment in time August is the most expensive month. These prices are determined by multiple factors and booking in advance can help keep costs down if your schedule is not as flexible.

  • How does Cheapflights help users find flights from Panama City?

    Deals for flights from Panama City are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

  • Why should you use Cheapflights to find cheap flight tickets from Panama City?

    Cheapflights simply makes it quick and affordable to book flights from Panama City by bringing together all flight options from hundreds of airlines and agencies online — and we put them in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

  • Can Cheapflights find flights from Panama City with no change fees?

    Certainly. Search results for flights from Panama City shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

  • Can Cheapflights notify me if prices for flights from Panama City become cheaper?

    Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

See more FAQs

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama City?

Deals for flights from Panama City are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Panama City?

Cheapflights simply makes it quick and affordable to book flights from Panama City by bringing together all flight options from hundreds of airlines and agencies online — and we put them in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

Can Cheapflights find flights from Panama City with no change fees?

Certainly. Search results for flights from Panama City shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Panama City become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.