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R12 654+ Cheap flights from Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — CPT
Mar 5 — Mar 121
1 adult

What to know about flights from Panama

Discover essential information about flights departing from Panama, including flight schedules, destinations, airlines operating at the Panama airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 28 February 2025.

Good one-way deal

R2 947 or less
Price to beat on a one-way flight from Panama.
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Find flights from Panama

Cheapest flights from Panama
Explore the most affordable flight options available from Panama. Find the lowest fares based on data from user searches, with prices last updated on 28 February 2025.

Wed 12/311:35PTY - JNB
2 stops38h 55mMultiple Airlines
Wed 19/320:25JNB - PTY
2 stops38h 47mMultiple Airlines
Deal found 26/2R19 848
Wed 19/311:35PTY - CPT
2 stops45h 35mUnited Airlines
Tue 15/418:05CPT - PTY
2 stops47h 36mUnited Airlines
Deal found 27/2R24 202
Sun 1/622:29PTY - JNB
2 stops51h 06mUnited Airlines
Sun 8/615:05JNB - PTY
2 stops29h 26mUnited Airlines
Deal found 27/2R24 368
Sun 16/319:50PTY - JNB
1 stop32h 05mTurkish Airlines
Wed 16/417:55JNB - PTY
2 stops31h 25mTurkish Airlines
Deal found 26/2R30 584
Wed 19/319:50PTY - CPT
1 stop33h 10mTurkish Airlines
Tue 15/416:35CPT - PTY
1 stop34h 25mTurkish Airlines
Deal found 27/2R32 447
Sat 29/318:45PTY - CPT
1 stop43h 25mKLM
Wed 9/423:00CPT - PTY
1 stop24h 50mKLM
Deal found 27/2R37 704
Sat 31/518:50PTY - JNB
1 stop43h 30mKLM
Sat 21/623:15JNB - PTY
1 stop24h 35mKLM
Deal found 26/2R37 741
Sat 31/519:55PTY - JNB
1 stop29h 30mAir France
Sat 21/618:50JNB - PTY
2 stops29h 00mAir France
Deal found 26/2R38 073
Mon 31/315:26PTY - CPT
2 stops37h 09mEmirates
Wed 9/413:05CPT - PTY
2 stops48h 24mEmirates
Deal found 27/2R39 088
Sat 29/320:50PTY - CPT
2 stops41h 20mMultiple Airlines
Wed 9/415:20CPT - PTY
2 stops32h 30mMultiple Airlines
Deal found 27/2R39 586
Sat 31/511:42PTY - JNB
3 stops50h 08mEmirates
Sat 21/613:25JNB - PTY
3 stops47h 59mEmirates
Deal found 26/2R79 633
Sun 1/613:20PTY - JNB
3 stops34h 40mAmerican Airlines
Sun 8/621:15JNB - PTY
2 stops46h 45mAmerican Airlines
Deal found 27/2R191 178

Find flights from Panama within your budget

Find flights departing from Panama that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 28 February 2025. In the last 7 days, Cheapflights users made a total of 594 507 searches

Fly to

Cape Town

Route

Depart

Return

Price

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Wed 12/3

11:35-9:30

2 stops38h 55m

Johannesburg OR Tambo

Wed 19/3

20:25-4:12

2 stops38h 47m

R19 848

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Wed 19/3

11:35-16:10

2 stops45h 35m

Cape Town Intl

Tue 15/4

18:05-10:41

2 stops47h 36m

R24 202

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sun 1/6

22:29-8:35

2 stops51h 06m

Johannesburg OR Tambo

Sun 8/6

15:05-13:31

2 stops29h 26m

R24 368

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sun 16/3

19:50-10:55

1 stop32h 05m

Johannesburg OR Tambo

Wed 16/4

17:55-18:20

2 stops31h 25m

R30 584

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Wed 19/3

19:50-12:00

1 stop33h 10m

Cape Town Intl

Tue 15/4

16:35-20:00

1 stop34h 25m

R32 447

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sat 29/3

18:45-21:10

1 stop43h 25m

Cape Town Intl

Wed 9/4

23:00-16:50

1 stop24h 50m

R37 704

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sat 31/5

18:50-21:20

1 stop43h 30m

Johannesburg OR Tambo

Sat 21/6

23:15-16:50

1 stop24h 35m

R37 741

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sat 31/5

19:55-8:25

1 stop29h 30m

Johannesburg OR Tambo

Sat 21/6

18:50-16:50

2 stops29h 00m

R38 073

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 31/3

15:26-11:35

2 stops37h 09m

Cape Town Intl

Wed 9/4

13:05-6:29

2 stops48h 24m

R39 088

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sat 29/3

20:50-21:10

2 stops41h 20m

Cape Town Intl

Wed 9/4

15:20-16:50

2 stops32h 30m

R39 586

Flights are sorted by cheapest return flights first.

Deals found on 27/2

Showing 1-10 of 18 results
1
2

Best time to book a flight from Panama

Have a flexible travel schedule? Discover the best time to fly from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama

Get recent, data-driven insights about flights from Panama including ideal travel times, pricing trends, and more.

What is the cheapest place to fly to from Panama?

The cheapest city to fly to from Panama is Quito Mariscal Sucr, with prices starting at R2 947. Explore other affordable destinations below.

Quito Mariscal Sucr

Quito Mariscal Sucr

From R160

Airline reviews for flights from Panama

Get insights into the airlines that provide service from Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing airline for your flight from Panama. In the last 7 days, Cheapflights users made a total of 594 507 searches.
Emirates
8,1
Very Good
3 250 reviews
Check prices

Crew

8,3

Entertainment

8,2

Food

7,9

Overall

8,1

Comfort

8,0

Boarding

8,1

Reviews

1 / 20

10,0
Excellent

Anonymous,Oct 2024

CPT - DXB

Overall a good experience. Can’t fault it. Good could have been a little better.

Emirates
8,1
Very Good
3 250 reviews
Emirates
8,1
Very Good
3 250 reviews
Check prices

Crew

8,3

Entertainment

8,2

Food

7,9

Overall

8,1

Comfort

8,0

Boarding

8,1

Reviews

1 / 20

10,0
Excellent

Anonymous,Oct 2024

CPT - DXB

Overall a good experience. Can’t fault it. Good could have been a little better.

KLM
7,8
Good
1 326 reviews
Emirates
8,1
Very Good
3 250 reviews
Check prices

Crew

8,3

Entertainment

8,2

Food

7,9

Overall

8,1

Comfort

8,0

Boarding

8,1

Reviews

1 / 20

10,0
Excellent

Anonymous,Oct 2024

CPT - DXB

Overall a good experience. Can’t fault it. Good could have been a little better.

United Airlines
7,4
Good
8 719 reviews
Emirates
8,1
Very Good
3 250 reviews
Check prices

Crew

8,3

Entertainment

8,2

Food

7,9

Overall

8,1

Comfort

8,0

Boarding

8,1

Reviews

1 / 20

10,0
Excellent

Anonymous,Oct 2024

CPT - DXB

Overall a good experience. Can’t fault it. Good could have been a little better.

Turkish Airlines
7,3
Good
3 809 reviews
Emirates
8,1
Very Good
3 250 reviews
Check prices

Crew

8,3

Entertainment

8,2

Food

7,9

Overall

8,1

Comfort

8,0

Boarding

8,1

Reviews

1 / 20

10,0
Excellent

Anonymous,Oct 2024

CPT - DXB

Overall a good experience. Can’t fault it. Good could have been a little better.

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Direct flights from Central America

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Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 28 February 2025.

  • How does Cheapflights help users find flights from Panama?

    Cheapflights helps you search for flights from Panama via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

  • Why should you use Cheapflights to find cheap flight tickets from Panama?

    It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama.

  • Can Cheapflights find flights from Panama with no change fees?

    Yes, we can. To see specific flights from Panama with no change fees, users can toggle flexible booking options after using the search form above to find flights.

  • Can Cheapflights notify me if prices for flights from Panama become cheaper?

    Yes, Cheapflights has a feature called Price Alerts, which offers users the ability to be notified when flight prices change. Track prices for your flight from Panama today and book when you’re ready!

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Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama?

Cheapflights helps you search for flights from Panama via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

Why should you use Cheapflights to find cheap flight tickets from Panama?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama.

Can Cheapflights find flights from Panama with no change fees?

Yes, we can. To see specific flights from Panama with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Panama become cheaper?

Yes, Cheapflights has a feature called Price Alerts, which offers users the ability to be notified when flight prices change. Track prices for your flight from Panama today and book when you’re ready!

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